InDevR partners with Aldevron to describe how the VaxArray 5′CapQ assay can be used to measure intact mRNA in a single assay to streamline bioprocess development.
This disrupts the translation initiation complex and provides degradative enzymes with access to the 5′ cap and remaining RNA body. The intimate relationship between mRNA decay and translation ...
and Furuichi et al., revealed that certain viral and eukaryotic mRNAs have a cap — a methylated guanosine residue linked to the 5′ end of mRNA through an inverted 5′ to 5′ triphosphate bridge.