As AAV vector applications in gene therapy continue to expand ... as well as facilitating the successful translation of gene therapies from the laboratory to clinical applications. The AAV Titration ...
Organoids were cultured from healthy donor iPSC sources and differentiated using the human iPSC-derived Cerebral Organoid ...
ReGenX's AAV Vector Technology gives extremely efficient and stable gene expression in neonatal and adult animals, and can be used to create disease models and to study gene function and target ...
vector genome titer, and capsid titer. Fig 1. The Vericheck ddPCR Empty-Full Capsid Kit method. DNase treatment removes external DNA. Probes then specifically bind to AAV capsids. Oligos on these ...
With the absolute quantification provided by Bio-Rad’s Droplet Digital™ PCR, the Vericheck ddPCR Empty-Full Capsid Kits require minimal volumes of either crude lysate or purified samples to deliver ...
Previous efforts to circumvent the problem of the size limitation imposed by the AAV vector have focused mainly on altering the candidate genes into ‘mini-expression cassettes’ suitable for ...