This organoid contains the three main types of pancreas cells: acinar cells, ductal cells, and endocrine cells. Each of these cells plays a vital role. Acinar cells release enzymes that help break ...

The results revealed that VB12 directly protects acinar cells from necrosis during the early stages of acute pancreatitis and ...

Acute pancreatitis (AP) is a gastrointestinal disorder characterized by inflammation and necrosis of the pancreatic acinar cells. Mitochondrial homeostasis is key to energy metabolism and redox ...

Genomic Characterization and Prognostic Significance of Human Epidermal Growth Factor Receptor 2–Low, Hormone Receptor–Positive, Early Breast Cancers From the BIG 1-98 and SOFT Clinical Trials The ...

Pancreatic ductal adenocarcinoma (PDAC) develops in the exocrine compartment of the pancreas, which is comprised of ductal and acinar cells. PDAC is associated with two major types of asymptomatic ...

Ever since George Palade's pioneering studies of zymogen secretion from pancreatic acinar cells, the underlying molecular mechanisms of vesicle-mediated protein transport have captivated cell ...

EVEREST-2: A seamless phase 1/2 study of A2B694, a logic-gated Tmod chimeric antigen receptor T-cell (CAR T) therapy, in patients with pancreatic cancer (PANC) or other mesothelin (MSLN)-expressing ...