Validation results showed that the antioxidants activate the AMPK enzyme (adenosine monophosphate-activated protein kinase), an intracellular energy sensor, and inhibit the production of reactive ...

The phosphate generally comes from adenosine triphosphate (ATP ... fluorescent biosensor allows real-time visualization of PKN kinase activity, revealing sustained activity at the plasma membrane ...

Announcing a new article publication for BIO Integration journal.   Diabetes, a common metabolic condition, poses a substantial health burden worldwide. To revolutionize diabetes management, enhance ...

In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...

Here, the authors employed 19 F NMR and Gaussian accelerated MD simulations to determine the conformational landscape of the adenosine-A2A ... is a receptor tyrosine kinase essential for the ...