MPI scientists, led by research group leader Jan Deussing, wanted to know what function the risk gene adenylyl cyclase 2 has ...

The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme, becomes activated by G-protein molecules associated with the adrenergic receptor. Adenylyl cyclase creates ...

including almost all of the genes of the cyclic AMP (cAMP) signaling pathway including the Git2 adenylyl cyclase that produces cAMP. Additional studies showed a role for the Cgs2 phosphodiesterase ...