Background Hypophosphatasia (HPP) is a rare inherited disorder of bone and mineral metabolism, caused by mutations in the ALPL (alkaline phosphatase liver type) gene, with reduction of activity of the ...

Scientists from the University of Michigan, US have discovered that at least six herbal supplements like Ashwagandha, Red ...

buckshealthcare.nhs.uk A 32-year-old overweight asymptomatic man was found to have a persistently raised serum alkaline phosphatase at 250–300 U/l (normal range <130). Other liver function tests were ...

Only a few studies have investigated the significance of a mild, isolated elevation of alkaline phosphatase. Because 1% to 9% of people without symptoms have elevated liver enzymes, extensive ...

Laboratory tests revealed elevated concentrations of aminotransferases, bilirubin, γ-glutamyltransferase and alkaline phosphatase. Liver biopsy revealed histological evidence of subacute ...

The diagnostic value of primary biliary cholangitis (PBC)-specific antibodies in patients with elevated alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) levels, and other identifiable ...

The total alkaline phosphatase levels were determined in 118 patients with adult coeliac disease, 65 of whom had evidence of osteomalacia. The secretor and blood group status, intestinal isoenzyme, ...

China: A recent analysis of data from the National Health and Nutrition Examination Survey (NHANES) 2009–2014 has found a ...

Serum alkaline phosphatase (ALP) levels are routinely included in liver function testing (LFTs) and when measuring ‘bone biochemistry’. This paper discusses the evidence base for its measurement in ...

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl ...

Chlorcyclizine shows promise in reducing protoporphyrin-IX accumulation and liver damage in erythropoietic protoporphyria, ...