Two classes of commonly prescribed oral antibiotics are associated with the greatest risk for severe drug rashes that can lead to emergency department visits, hospitalizations and even death ...
amoxicillin 50mg/kg + probenecid 25mg/kg as a single dose. Cephalosporin, imipenem or other allergy: not recommended. Discontinue if allergic reaction or drug-induced enterocolitis syndrome occurs.
This confirmed the diagnosis of an anti-TNF-agent-induced psoriasiform skin rash. The skin manifestations caused the patient sufficient distress to prevent further use of a TNF antagonist.