The medications discussed in this article have very different mechanisms of action, but all were designed with one primary goal: to alter the balance between procoagulant and anticoagulant ...

UFH is one of two agents that comprise conventional anticoagulant therapy. It is considered a natural agent and has been the standard of care for many years. Its mechanism of action is depicted in ...

Now, in our eighth 'Case history' article, Gustafsson and colleagues discuss the discovery of ximelagatran, the first oral anticoagulant with a novel mechanism of action to be developed in half a ...

Overall, these studies underscore the importance of understanding the genetic basis of anticoagulant resistance in rodent populations. As resistance mechanisms evolve, pest control strategies must ...

Abelacimab, a factor XI inhibitor, demonstrated a 62–69% reduction in major bleeding compared to rivaroxaban in atrial fibrillation patients at moderate-to-high stroke risk, with comparable safety and ...