Figure 1: Structure and antifungal activity of amphotericin B and a rationally designed synthetic probe. Given the fact that no conclusive evidence had been provided for the current amphotericin B ...

Secondary objectives included assessing the frequency of changes in antifungal therapy due to infusion-related reactions involving amphotericin B formulations, evaluating mycological cure rates in ...

Aspergillosis is an infection caused by Aspergillus, a fungus naturally present in the environment. Most people come into ...

Since amphotericin B is the most effective drug available to treat a variety of systemic fungal infections, every effort should be directed at preventing renal damage when the clinical situation ...

“It is doubly tragic,” he said, “That these antifungals have been used since the late 1950s in the case of amphotericin B. Yet the systems for delivering these drugs to the most needy are still not in ...

Background: Invasive candidiasis is increasingly prevalent in premature infants and seriously ill children, and pediatric data on available antifungal ... with liposomal amphotericin B (3 mg ...

Medindia neither buys nor sells drugs. Amphotericin B (Ampholip 10) is an antibiotic, prescribed for life-threatening fungal infections. It is also effective in treating leishmaniasis. Newer ...

In some cases, intravenous antifungal medications like amphotericin B are recommended. Many systemic fungal infections require months of treatment. In some cases, treatment is lifelong.

F2G and Shionogi are also running a phase 3 trial called OASIS that is comparing olorofim to Astellas’ AmBiome (liposomal amphotericin B) – a standard therapy for resistant fungal infections ...

Amphotericin B (AmB) is the drug of choice for progressive and potentially life-threatening fungal infections of the abdomen and heart valves, fungal pneumonia, and leishmaniasis, a neglected ...

UK biotech F2G has raised $100 million as it prepares to refile its olorofim candidate for invasive fungal infections ... to Astellas' AmBisome (liposomal amphotericin B) in invasive aspergillosis ...