Antigen-presenting cells work to present peptides derived from exogenous and endogenous antigens to circulating T cells, sparking off an immune response. Dendritic cells are unique amongst antigen ...
A stable interaction between antigen-presenting cells (APC) and T cells is dependent not only on the absolute affinity between the T-cell receptor (TCR) and its ligand but also on the relative ...
You could target the aggressor T-cells directly. Or you could target the antigen presenting cell that orchestrates the immune attack." The ultimate goal, Cochrane said, would be a "living ...
These projects involve the production of plasmid DNA vaccines; the generation of genetically modified dendritic cells and genetically targeted T lymphocytes; as well as the engineering of artificial ...
Our research group aims at identification of cellular mechanisms, which could be used to enhance adaptive immune response in inflammation-associated disease conditions via controlled expansion of ...
The normal cornea contains a relatively small population of immune cells, which are mainly antigen-presenting cells, and lacks blood and lymph vessels. These qualities are partially responsible ...