This syndrome is referred to as aspirin-induced asthma (AIA). The pathogenesis of AIA has implicated both the lipoxygenase (LO) and the cyclooxygenase (COX) pathways. By inhibiting the COX pathway ...

Prostaglandins are powerful signaling agents in the human ... aspirin. It is now known that all of these drugs block the activities of cyclooxygenase (COX), enzymes that act early in the pathways ...