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Astrocytes are fundamental players in the regulation of synaptic transmission and plasticity. They display unique morphological and phenotypical features that allow to monitor and to dynamically ...

The fundamental astrocyte-neuron computer model for self-repair proposed in this project was proven in an earlier EPSRC eFutures funded project (EFXD12011) where it was demonstrated that the ...

Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...

astrocyte stock illustrations Six types of gliocytes in the central and the peripheral nervous system: oligodendrocyte, astrocyte, ependymal cell, microglia, Schwann and satellite cell. Cells of human ...

Activating the astrocyte ensemble specifically stimulates synaptic activity or communication in the corresponding neuron ...

2001). Cholesterol supply to neurons might be reduced in HD astrocytes by contributing to neuronal dysfunction in HD neurons. Methods and results Here we show that primary astrocytes obtained from ...

This interaction enables the astrocyte to modulate the information flow from presynaptic to postsynaptic cells in a manner dependent on previous activity at this and other nearby synapses. Our model ...

2020). Microglia can also play a significant neuroprotective role during excitotoxic events. When challenged with glutamate, tri-cultures have significantly less neuronal cell loss compared to ...

Neuron, Cell Press’s prestigious neuroscience ... aging processes like white matter deterioration and how aged astrocytes impact brain function. “While the causes of disease are multifactorial ...