It receives inputs from the limbic system and the basal ganglia and sends outputs to midbrain areas that are involved in the release of dopamine (the substantia nigra pars compacta and ventral ...

Dopaminergic neurons in the basal ganglia normally fire in a random ... Figure 2: Continuous firing of substantia nigra pars compacta neurons and constant striatal dopamine concentrations in ...

Idiopathic Parkinson’s disease (IPD) is a central nervous system disorder affecting the basal ganglia that is caused by death of dopamine-producing cells in the substantia nigra. Although IPD is ...