Using unnatural base pairs, researchers have site-specifically biotinylated RNA, allowing them to immobilize an aptamer on a chip and detect its interaction with a target protein. Experiments with ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

"RNA interference is a well-known type of gene regulation in which cells can turn down the expression of a gene by expressing a small RNA that can base pair with the RNA of the target gene. This type ...

"RNA interference is a well-known type of gene regulation in which cells can turn down the expression of a gene by expressing a small RNA that can base pair with the RNA of the target gene.

When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA). This process takes place in the nucleus and occurs in a series of stages. The two ...

RNA-based therapies, such as small interfering RNA (siRNA) and antisense oligonucleotide (ASOs), rely on the specific base-pairing properties of uracil to target and regulate disease-related genes. In ...

Biologists at Indiana University Bloomington have shown that the surfaces of plant leaves are coated with a diverse array of RNA molecules. The finding suggests that the RNA present on the leaf ...