Beta-lactam antibiotics are the most widely used class of drugs for the treatment of bacterial infections. They include penicillin and its derivatives, such as methicillin and amoxicillin, as well as ...

It is a first-generation cephalosporin antibiotic, meaning that it was among the first cephalosporins developed. It is also ...

First-line antibiotics for uncomplicated UTI remain more effective than fluoroquinolones and beta-lactams in a retrospective ...

Beta-lactamase inhibitors are designed to overcome a key resistance mechanism that allows pathogens to protect themselves from beta-lactams, one of the most commonly-used antibiotic classes.

The team have identified the structural basis for the differences in activity of class A enzymes, the most widely distributed beta lactamases, against carbapenem antibiotics, and used this information ...

Pfizer’s Emblaveo has been approved in the EU with a first-in-class indication in multidrug-resistant (MDR) infections. The drug – a combination of beta-lactam antibiotic aztreonam with beta ...

The drug combination involves cefepime, a widely used beta-lactam (BL) antibiotic with over two decades of proven safety and effectiveness against susceptible gram-negative and gram-positive ...