“Our findings demonstrate that MBS8 can turn a ‘cold’ tumor, with low levels of inflammation and CD8 T cells, into a ‘hot’ tumor that is infiltrated by cancer killing CD8 T cells ...

“Furthermore, DR5-scFv sEVs significantly inhibited MDSCs and cancer-associated fibroblasts (CAFs) in the TME and activated CD8+ T cells in organotypic patient-derived melanoma slice culture ...

Therapeutic mRNAs offer great potential as a versatile and precise tool against cancer ... lipid-based nanoparticles (LNPs). To find the best formulation of LNP to bring mRNA into cells, the ...

Researchers at the University of Colorado Anschutz Medical Campus have discovered that some CAR-T cells engineered to fight cancer and other ... functional states of CD8+ CAR T cells during ...