在本次研究中，康涅狄格大学团队则专门设计了仅分析肿瘤新抗原特异性CD8 + T细胞的实验系统，并根据CD8 + T细胞的TCR亲和力高低进行分类，再分别 ...

A groundbreaking study published in Nature reveals how tissue-resident memory CD8 T cells in the small intestine take on ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8 + T cell division for the generation of memory precursor cells.

Scientists from A*STAR Genome Institute of Singapore (A*STAR GIS) have uncovered that a key enzyme – P4HA1 prolyl hydroxylase, is strongly induced in CD8+ T cells in solid cancer, the primary immune ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Proper immune system function is paramount for human survival against infectious disease ... Once acquired infection persists for life requiring continuous life long cellular immunity (CD8 memory T ...