This image shows a schematic diagram of the highly efficient CRISPR/Cas system, which leads to super efficient targeted insertion (knock-in) of a long donor insert into mouse genome.

The precise insertion of DNA sequences using the homology-directed repair (HDR) pathway is one potential use of the CRISPR/Cas genome ... found to be 80% higher. GFP KI at RAB11A Locus in HEK293 ...

CRISPR-based homology-directed repair (HDR) is an invaluable tool to facilitate specific mutations in a genomic region of interest in research studies. While many methods have been reported for ...