Several tumour-suppressor proteins monitor intrinsic and extrinsic signals and integrate these inputs to decide whether the cell should remain in a quiescent state or enter into the cycle of ...

Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been ...

Glycolysis is an important sugar degradation pathway that cancer cells in particular depend on. Scientists at the German Cancer Research Center (DKFZ) have now shown that liver cancer cells in mice ...

CDKN1B 5′UTR mediates its cell cycle-dependent translation and several proteins can bind the CDKN1B IRES to modulate its translation. micro-RNA-mediated inhibition of p27 translation emerges as ...

Researchers from University of Athens and National Centre For Scientific Research “Demokritos” have reported preclinical data from a study that aimed to assess the novel cryptochrome-2 (CRY2) ...

Schmidt Chair of Cancer Research; Member, Memorial Sloan Kettering Cancer Center; Professor, Weill Graduate School of Biomedical Sciences, Cornell University My long-term interest is to understand how ...

Trilaciclib significantly reduced chemotherapy-induced myelosuppression in extensive-stage small cell lung cancer, which ...

Researchers identify distinct molecular and immune profiles that impact the prognosis of patients with metastatic pancreatic ductal adenocarcinoma.

Discover the intricate link between obesity and cancer, with insights into hormonal, inflammatory, and microbiota factors.

Esophageal squamous cell carcinoma (ESCC) is a severe health threat, being a predominant subtype of esophageal cancer and contributing significantly to cancer-related mortality globally. Despite ...