Selecting an appropriate mouse model is one of the most important decisions a pre-clinical researcher can make. Which is best suited for immuno-oncology? Cancer research and drug discovery has ...

Our laboratory is interested in the use of mouse models of prostate cancer to explore the pathogenesis of prostate cancer and its response to treatment. We have used the SV-40 based TRAMP model of ...

The study, conducted in a mouse model of lung cancer, is published in Nature. "We know that as people get older, they're more likely to get cancer," says study first author Xueqian Zhuang ...

Their study suggests that a high-fiber, plant-based diet can delay the disease in individuals at risk. The findings were ...

Cancer immunotherapy drugs called immune checkpoint inhibitors take the brakes off the body’s immune system, allowing it to ...

Long focused on antioxidants, researchers are now exploring a new route to combat prostate cancer: pro-oxidants.

By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...

Everything inside the mouse – its nerves, tissues and organs – are made invisible by a chemical process A new scanning method involving a see-through mouse could improve how cancer drugs are ...

In the new study, Scheff and her team found that morphine suppressed response to anti-PD1 immune checkpoint therapy in a mouse model of oral cancer. Animals that received morphine had fewer cancer ...

Photoimmunotherapy is an innovative cancer treatment that combines phototherapy with immunotherapy to selectively target and destroy cancer cells.

Calcipotriol-plus–5-FU therapy activates immune pathways, offering long-lasting protection against squamous cell carcinoma by ...