The researchers compared the effects of a cathepsin K inhibitor and alendronate in ... K had an inhibitory effect on periarticular osteoporosis, comparable to that of alendronate, but also ...

is currently in Phase III studies for osteoporosis prevention and has caused some excitement with Phase II data. ONO-5534 is a cathepsin K inhibitor that inhibits bone resorption without affecting ...

Cathepsin K inhibitors and RANKL antibodies have been ... mass represent exciting opportunities for future drug development. Osteoporosis results in over nine million fractures per year at a ...