The researchers compared the effects of a cathepsin K inhibitor and alendronate in ... K had an inhibitory effect on periarticular osteoporosis, comparable to that of alendronate, but also ...

Cathepsin K inhibitors and RANKL antibodies have been ... mass represent exciting opportunities for future drug development. Osteoporosis results in over nine million fractures per year at a ...

is currently in Phase III studies for osteoporosis prevention and has caused some excitement with Phase II data. ONO-5534 is a cathepsin K inhibitor that inhibits bone resorption without affecting ...