在线发表了题为"Nanobody-based Naturally Selected CD7-Targeted Chimeric Antigen Receptor T Cell Therapy for Acute Myeloid Leukemia"的研究论文。这项研究成果标志着在急性髓 ...

Researchers found that naturally-occurring CD7-negative T cells avoid self-destruction and are good effectors in CAR T therapy for T cell blood cancers. Deanna earned their PhD in cellular biology ...

Genomic DNA isolated from CUTLL1 cells and from the corresponding primary T-cell lymphoblastic lymphoma ... of CD4 and CD8 as well as CD2, CD5, CD7, surface CD3 and TCRαβ (Figure 1).

The first step was to disable the T-cells' natural targeting system to prevent them from attacking Alyssa's body. The second edit removed a specific marker, called CD7, from the T-cells to ensure ...