flies), cancer and normal mammalian cell lines, and rodents and higher mammals we have a detailed understanding of the conserved mechanisms by which cells choose to enter and exit the cell cycle, and ...

A diverse set of cytoskeletal reorganization genes exhibit cell-cycle–dependent regulation, indicating that biological pathways are redirected for the execution of cell division. Many genes ...

The observations suggested that regulation of the cell cycle is conserved throughout eukaryotes ... effective strategies for intervention in cancer and other growth abnormalities, such as ...

When gene regulation fails ... cells will proliferate out of control or resist cell death pathways, two key features of cancer. Their results were published in Genes & Development.