7 It therefore appeared reasonable to investigate systematically the chromosomes in a group of patients to determine if any abnormalities could be found in this condition. Constitutional aplastic ...

An example of a balanced structural change is the Philadelphia chromosome translocation previously ... A new consistent chromosomal abnormality in chronic myelogenous leukemia identified by ...

[44] Combining a limited karyotype with the more objective microarray data will allow for a clearer interpretation for any disease-causing chromosome abnormalities, if any, in the fetus undergoing ...

Each chromosome pair viewed in a karyotype appears to have its own distinct "bar code" of bands. What changes do scientists look for in a karyotype when diagnosing diseases and disorders?

ISBN 0 195 14960 2 (hardback). The third edition of this outstanding text is an essential resource for counselling for families with chromosome abnormalities. This book has been extensively updated ...

On the rare occasion that errors do occur, cells with abnormal chromosome numbers are rapidly cleared. But cancer is different. Tumor cells are remarkably tolerant of chromosomal abnormalities, and ...

Now that certain human disorders have been linked with chromosome abnormalities, it is desirable to examine large numbers of cells for such abnormalities. A computer regime has been devised for ...

This process involves two rounds of division, meiosis I and meiosis II, and includes unique events like chromosome pairing, crossover, and independent assortment, which increase genetic diversity in ...

Science has revealed some of the secrets of the X chromosome, but many remain. In humans, female cells contain two X ...

Microarray analysis identifies more chromosome abnormalities than traditional karyotyping in prenatal testing. Microarrays will also identify findings of unclear clinical significance that should ...