7 It therefore appeared reasonable to investigate systematically the chromosomes in a group of patients to determine if any abnormalities could be found in this condition. Constitutional aplastic ...

Chromosome abnormality is the condition in a cell or organism where the number of chromosomes or the structure of any chromosome differs from the normal karyotype. When the variant genotype is not ...

Each chromosome pair viewed in a karyotype appears to have its own distinct "bar code" of bands. What changes do scientists look for in a karyotype when diagnosing diseases and disorders?

A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities ...

[44] Combining a limited karyotype with the more objective microarray data will allow for a clearer interpretation for any disease-causing chromosome abnormalities, if any, in the fetus undergoing ...

Now that certain human disorders have been linked with chromosome abnormalities, it is desirable to examine large numbers of cells for such abnormalities. A computer regime has been devised for ...

On the rare occasion that errors do occur, cells with abnormal chromosome numbers are rapidly cleared. But cancer is different. Tumor cells are remarkably tolerant of chromosomal abnormalities, and ...

Microarray analysis identifies more chromosome abnormalities than traditional karyotyping in prenatal testing. Microarrays will also identify findings of unclear clinical significance that should ...

Researchers aim to continue studying the role of the X chromosome in brain aging, and whether it can explain people’s risk of ...

The study, published today in Nature, discovered that at least 3% of normal cells from breast tissue in 49 healthy women contain a gain or loss of chromosomes, a condition known as aneuploidy, and ...