All participants crossed over to the other regimen 7–14 days later. The ciprofloxacin concentration in serial blood and urine samples collected during the 24 h period after the second antibiotic ...

The mean maximum concentration, mean area under the plasma-versus-concentration curve, and mean amount of ciprofloxacin excreted in urine were similar between the two treatments and met strict ...

Ciprofloxacin is widely prescribed for the ... This is an important observation,because fluoroquinolones exhibit concentration-dependent bactericidal activity, and reductions in bioavailability ...