It is well known that codon bias and gene expression ... These findings support the hypothesis that strong secondary structure at the 5′ end of an mRNA blocks ribosome binding and delays ...

This portion of mRNA is located between the first nucleotide that is transcribed and the start codon (AUG ... Begins After the Assembly of a Complex Structure The translation of mRNA begins ...

By focusing on diseases where precise control of protein expression can yield significant therapeutic benefits, we aim to maximize the impact of our mRNA-based interventions. One example is to tackle ...