When they failed to do so, they were given an unpredictable stimulus that was longer and more intense, resulting in disruption to the culture. The neurons soon learned to avoid the disruptive stimuli ...
The researchers obtained cells from ALS patients, and used them to culture neurons. These neurons, which carried C21orf2 mutations, had fewer cilia, and the cilia they did have were abnormally short.
Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...
If culture techniques stress a mammalian neuron ... In Griswold's experiments, the chemical that is usually used for imaging neurons caused the nanopearls to disappear, possibly explaining ...
One strong strategy is to use a culture system. Coculture of dorsal root ganglion neurons and Schwann cells can promote efficient myelin formation in vitro (Figure 1E). Researchers can modify the ...
These ensembles are coordinated groups of neurons firing together in specific regions of the brain, including the visual, auditory, and somatosensory cortices. Their activity patterns aren’t ...
Neuroscientists have identified that the receptor IL-1R1 plays a critical role in enabling neurons to directly communicate with the immune system. The new study provides the most detailed mapping of ...
Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.
Very few neurons remained at the site of MGE transplantation ... for 24 hours at 37°C in a tissue culture incubator (5% CO 2). Sections were then fixed in 3% paraformaldehyde, wet mounted ...
SARS-CoV-2 can infect human neurons in cell culture and in the brain of transgenic mice expressing the human receptor of the virus, ACE2, in the respiratory epithelium (K18-hACE2 mice). The mechanisms ...