The superfamily 1 (SF1) and SF2 enzymes are non-hexameric enzymes possessing both helicase and single-stranded DNA (ssDNA) translocase activities, as well as the ability to displace proteins from DNA.

How does the cell protect these strands from damage? How would you identify the protein that serves as a connector between DNA helicase and pol-a/primase? A simple yet often effective approach is ...

Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during ...

To prevent the accumulation of unreplicated gaps in the nascent DNA, when the leading-strand polymerase pauses the rate of the DNA helicase unwinding the parental template is reduced to about 15% of ...

in controlling fork progression and origin activation by inhibiting the activities of the replicative DNA helicase, CMG (Cdc45-MCM-GINS), and the cell cycle-regulated protein kinase, DDK ...

Researchers have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer. The research uncovers the vital role ...

A search for Npw38-interacting molecules revealed that Npw38 can interact with NpwBP, DNA helicase, RNA helicase, RNA, and single-stranded DNA to form a nuclear protein complex which may be involved ...

Image 1. PICH acts like a lookout, spotting and attaching to tiny DNA threads called ultrafine anaphase bridges (UFBs). When ...

The small molecule works by inhibiting ALC1 (chromodomain-helicase-DNA-binding protein 1-like), a chromatin remodeller and DNA helicase also involved in DNA repair. In what Schomburg terms a ...