Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression. This straightforward experiment demonstrated that it was ...

Muscle stem cells: Muscle stem cells, or satellite cells, decrease in number as we age. In elderly-human cells DNA methylation suppresses the expression of some genes, including sprouty 1, an ...

Changes in DNA methylation patterns occur early during oncogenesis, and each type of cancer has its own methylomic signature. Technological advances in methylation sequencing, or methyl-seq, allow ...