The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins ... often resulting in the methylation and pseudouridylation ...

The different building blocks can affect the complementarity of the RNA molecules, alter their structure, and enable the binding of specific proteins that mediate various biochemical and cellular ...

Yoshiki Ochiai, the paper's first author and Ph.D. student in the Protein Engineering and Evolution Unit, tried to improve RNA methylation activity of a bacterial non-site-specific DNA ...

A type of RNA, known as messenger RNA (mRNA), functions as the intermediate 'messenger' that carries information from DNA to make proteins - the basic building blocks of cellular components.

Modifications to histones, such as acetylation and methylation, can affect the accessibility of DNA to transcription factors and influence gene expression. In addition to protein-coding genes, the ...

However, RNA is typically single-stranded and serves various functions, such as coding for proteins (mRNA), transferring amino acids ... Further oxidized forms of 5hmC that are intermediates in the ...

These findings suggested that heat shocking induced changes in the chromatin conformation that reduced protein-DNA contacts. Next, the team tested whether the migration pattern differences they ...

bringing the simulated performance closer to that of a motor protein. The engineered motor, with redesigned DNA/RNA sequences and a 3.8-fold increase in hybridization rate, achieved a speed of 30 ...

Epigenetics involves how DNA — the blueprint used to build the proteins and molecules that make up our bodies — is read ...

A type of RNA, known as messenger RNA (mRNA), functions as the intermediate 'messenger' that carries information from DNA to make proteins -- the basic building blocks of cellular components.

and on post-translation histone and DNA modifications impacting on epigenetic regulation. Additional areas include RNA-mediated events ranging from cofactor recognition by riboswitches, catalysis by ...