Ilixadencel consists of dendritic cells that have been activated with cytokines and toll-like-receptor ligands so they ‘act’ as if they have been infected by a virus. The cells are injected ...

A group of proteins in our body, known as G protein-coupled receptors ... help dendritic cells sample the gut for foreign ...

Ig-like receptors ILT3 and ILT4 can be activated ... was utilized in the production of this manuscript. Phenotype of dendritic cells (DCs) may determine the type of immune reaction generated ...

Dendritic cells (DCs ... By contrast, foreign antigens result in DC maturation and DC-induced T-cell activation. Inappropriate maturation of DCs due to infections or tissue injury may cause ...

A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod.

Researchers at MedUni Vienna have developed a combination therapy using systemic interferon-I and topical imiquimod.

Adenosine deaminase 2 (ADA2) has been identified as a regulator of toll-like receptor 9 (TLR9 ... protein that controls TLR9 activation in plasmacytoid dendritic cells (pDCs).

development by activating the Aldh1a2/Raldh2 gene in dendritic cells through the aryl hydrocarbon receptor (AhR) and PU.1/IRF4 pathways. Raldh2, encoded by the Aldh1a2 gene, is expressed in ...