Ilixadencel consists of dendritic cells that have been activated with cytokines and toll-like-receptor ligands so they ‘act’ as if they have been infected by a virus. The cells are injected ...

Blander and Medzhitov explored the function of Toll-like receptor (TLR) signaling in controlling the maturation of phagosomes in macrophages and dendritic cells. As the phagosome is the key ...

A group of proteins in our body, known as G protein-coupled receptors ... help dendritic cells sample the gut for foreign ...

A recent study carried out by a research team from the Paul-Ehrlich-Institut investigated the immunomodulating properties of ...

Ig-like receptors ILT3 and ILT4 can be activated ... was utilized in the production of this manuscript. Phenotype of dendritic cells (DCs) may determine the type of immune reaction generated ...

The results indicate that β-glucans can target the immune system and modulate pro-inflammatory responses. Their potential to suppress allergic reactions and offer new approaches to allergy treatment ...

A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod.

Researchers at MedUni Vienna have developed a combination therapy using systemic interferon-I and topical imiquimod.

development by activating the Aldh1a2/Raldh2 gene in dendritic cells through the aryl hydrocarbon receptor (AhR) and PU.1/IRF4 pathways. Raldh2, encoded by the Aldh1a2 gene, is expressed in ...