Allogeneic dendritic cells provide both ‘stranger’ and ‘danger’ signals to the immune system that are crucial for it to sense a cell-associated threat such as cancer. These signals ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

The cells of the immune system are the guardians of these organisms – able to distinguish friend from foe and self from nonself. To accomplish this task in an organism with perhaps trillions of cells, ...

Cell-cell interactions help drive tolerogenic or inflammatory responses to the maelstrom of antigens passing through the gut.

gp96 is a powerful immune stimulator that directs antigen cross-presentation and enhances T cell costimulation on activated dendritic cells ... s natural immune system to treat cancer, ...

The immune system has evolved to mount immune responses ... may result in chronic inflammation or autoimmunity. Dendritic cells (DCs) actively participate in maintaining this balance.

known as conventional type 1 dendritic cells (cDC1s). These cells, located in parts of the gut like the ileum, can activate ...

A recent study carried out by a research team from the Paul-Ehrlich-Institut investigated the immunomodulating properties of ...

Effective for local tumors and distant metastases Immunotherapies use the body's own immune system to fight cancer cells. Plasmacytoid dendritic cells (pDCs), which are activated by Imiquimod via TLR7 ...

liver tissue cells and created immune tolerance between two allogeneic mice Liver tissue Interferon-regulatory factor-8 is essential for differentiation and function of dendritic cells and thus for ...

But T cells do not work alone; they rely on activation from other immune cells, particularly antigen-presenting cells (APCs) such as dendritic cells—the main T cell activators.

The results indicate that β-glucans can target the immune system and modulate pro-inflammatory responses. Their potential to suppress allergic reactions and offer new approaches to allergy treatment ...