LTβR –induced non-canonical NFκB activation in various stromal subsets within the SLOs is obligatory for the full differentiation of marginal reticular cells (MRC), follicular dendritic cells ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

Dr. Smythies earned her B.Sc. (Hons), A.K.C. at Kings College, London University, England and her Ph.D. at Wye College, London University. She did postdoctoral fellowships in the Department of ...

including dendritic cells and macrophages. Clinical features of herpes stromal keratitis Herpes stromal keratitis (HSK) is the most common cause of infectious corneal blindness in developed ...

Dendritic Cells (DCs): While exosomes can prime DCs to activate T cells, they also inhibit DC maturation and antigen presentation in advanced stages of HCC, contributing to immune suppression.

NEW YORK, Jan. 16, 2025 /PRNewswire/ -- The Food and Drug Administration (FDA) approved the first mesenchymal stromal cell (MSC) therapy, RYONCIL®, indicated for steroid-refractory acute graft ...