We investigate how the composition and dynamics of basement membrane, a specialised form of ECM, are regulated during tissue development and how they are altered during tumorigenesis. We are ...
This burgeoning area of research and development has yielded tremendous scientific advances. Thanks to the growing understanding of cancer biology we have seen considerable progress from ...
tumor microenvironment, mechanisms of drug sensitivity and resistance, and epigenetic sources of tumorigenic traits. We draw from fundamental mechanisms of cell and tissue development and homeostasis, ...
Genetically tailored treatment plans for children with a type of kidney cancer could help provide the most effective care while minimizing side effects as much as possible.
A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...
During development, many features of tissue and body form are shaped by the reorganization of cell populations ... These processes can also be coopted to promote the renegade cell movements that lead ...