but dexamethasone 6 mg (as the sodium phosphate salt) i.m. every 12 hours for four doses (single course) has also been used. The biological activity of the two agents is nearly identical ...

Dexamethasone provided 4 mg at every 6 hours, the usual initial dose—equivalent to 400 mg of cortisol per day—is about 20 times the normal rate of endogenous production. In patients who have ...