Understanding the signal transduction pathways involved in the differentiation process is vital to the success of this approach. GLP-1—a hormone secreted by the L cells of the small intestine ...

Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation ...

By utilizing intestine-wide cell imaging, the researchers found that the nutrient adaptation of stem cell size and the ...

The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...

An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures and villi in the intestine using a contact protein printing technique. This model ...

Differentiation of embryonic stem (ES) cells, which are originally totipotent ... injected into embryos can generate a wide variety of tissues including cells in the central nervous system, heart, ...

An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures and ...

A contact protein printing technique enables researchers to control the formation of villi in human gut models, making it ...

We discovered that interferon gamma (IFNγ) promotes hematopoietic stem cell (HSC) division and myeloid differentiation in a mouse model of Mycobacterium avium infection (Nature 2010). Furthermore, ...