Researchers from the Manchester Institute of Biotechnology and the Department of Chemistry at The University of Manchester ...

Enzymes are crucial to life. They are nature's little catalysts. In the gut, they help us digest food. They can enhance ...

A new ML-guided platform can design thousands of new enzymes, predict how they will behave in the real world, and test their ...

In traditional directed evolution approaches ... or when more than one property is being selected for. “We need the enzyme to be highly active, stable in the process, and tolerant of high ...

Several teams of two students create and characterize individual enzyme variants for a specifically designed research project, addressing a fresh set of questions every year. Thus, neither the ...

Enzyme-bound flavin cofactors have spectroscopic signals that directly report on the chemistry occurring in the active site, which we exploit in order to study their reaction mechanisms using ...

Using techniques like directed evolution, we can engineer enzymes to optimize them towards our desired activities by mimicking the natural selection process in the laboratory. To this end we are ...