To carry out the interaction assays, the bait proteins must be bound to beads. Transfer a portion of glutathione Sepharose 4B resin to a microcentrifuge tube. Use an amount of resin that is at ...

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

A new study from Moffitt Cancer Center could help doctors predict how well patients with a specific type of lung cancer will ...

PELSA is broadly applicable to diverse ligands including metabolites, drugs, and pollutants. The biochemical functions of proteins invariably involve interactions with ligands of some type ...

But yeast two-hybrid assays and coimmunoprecipitation, the two main techniques for generating "interactomes," maps of protein interactions on a proteome-wide scale, can leave gaping holes. The yeast ...

Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago, researchers developed a way to map these molecular connections. Mariella is an assistant editor at The ...

ACROBiosystems’ high-quality recombinant antigen proteins and ... anti-SARS-CoV-2 drugs and vaccines. Such kit products comprise SARS-CoV-2 antibody titer serologic assay kits, inhibitor ...

Antibody-drug conjugates (ADCs ... HE2-H5225) with an affinity constant of 1.07 nM as determined in a SPR assay. Image Credit: ACROBiosystems Loaded Trastuzumab on AHC Biosensor, can bind Human ...

A new study from Moffitt Cancer Center could help doctors predict how well patients with a specific type of lung cancer will respond to new therapies. The research, published in Clinical Cancer ...

TOKYO--(BUSINESS WIRE)--Axcelead Drug Discovery ... of targeted protein degraders, compound libraries, diverse high-throughput screening systems and profiling assay systems. Under the agreement ...

A new study from Moffitt Cancer Center could help doctors predict how well patients with a specific type of lung cancer will respond to new ...