How do bacteria, lacking a nucleus, organize and pack their genome into the cell? Supercoiling enables this but forces a different kind of transcription and translation in prokaryotes. Aa Aa Aa ...
"It appears that RapA and Rho work as complementary -- not redundant -- safeguards for genome stability when E. coli are subject to high-salt stress." The implications could be vast. Darst ...
We investigate this problem using synthetic cross-feeding interactions: by simply deleting two metabolic genes from the genome of Escherichia coli, we generated genotypes that require amino acids ...
These manipulations intend to introduce new functional features while meticulously balancing the native functions of replication, reproduction, and growth. Genome construction involves three basic ...
LBP-EC01 is a bacteriophage ‘cocktail’ that has been modified using CRISPR/Cas3 gene-editing to improve its ability to target the E coli genome. Lab studies have demonstrated it is ...