and thus resensitizing the receptor so that it can signal once again. Novel roles of endocytosis in ‘turning on’ signaling, especially turning on ERK activation were first appreciated ...

Shenoy et al., "β-Arrestin-dependent, G protein-independent ERK1/2 activation by the β2 adrenergic receptor," J Biol Chem, 281:1261-73, 2006. (Cited in 50 papers) The finding: In 2005, while screening ...

Intercontinental Exchange and RELX are among the stocks that are now expensive. We sell different types of products and services to both investment professionals and individual investors. These ...

inhibiting glucagon release, and promoting satiety. Dysregulated signaling of these receptors has been implicated in type 2 diabetes, obesity, and metabolic dysfunction-associated steatotic liver ...

5, 2025 /PRNewswire/ -- The American College of Clinical Pharmacology ® (ACCP) published a recent Position Paper entitled "Ensuring the Appropriate Use of Glucagon-Like Peptide-1 Receptor Agonists".