As humans do not synthesize dTDP-l-rhamnose, the four enzymes of its metabolic pathway represent very appealing ... the lack of a functional RmlD enzyme leads to the loss of serum resistance ...

They show the parasites that cause leishmaniasis are vulnerable via a different pathway for biosynthesis of their ergosterol, known as the CYP5122A1 enzyme. Therefore, azole antifungals targeting ...

Metabolic pathways are integrated and controlled enzyme-catalysed reactions within a cell. In animals, specific metabolic pathways can produce vitamins and haemoglobin. Metabolic pathways can be ...

Figure 1. Reconstruction of the L-rhamnose utilization pathways in bacteria. Solid gray arrows indicate enzymatic reactions, and broken arrows denote transport. Enzyme classes and families of ...