in various free and ligand bound states. For example, conformational changes in enzymes may be crucial for optimal function and may result from subtle movements, such as the rotation of a peptide ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme's ligand-binding site, interfering with ...

PELSA is a sensitive, versatile method for identifying ligand-binding proteins and sites in native systems without requiring ligand modification. It outperforms traditional approaches in sensitivity, ...