With the addition of a ligand-sensing aptamer sequence, a self-replicating RNA enzyme system enables general molecular detection, analogous to that of quantitative PCR. With the ultimate goal of ...

Optically pure alcohols are prevalent motifs in natural products and pharmaceuticals, driving the development of effective ...

which act as enzyme substrates or inhibitors, signaling molecules, allosteric modulators, structural anchors, etc. Monitoring protein-ligand interactions is thus essential for characterizing ...

Discover MFFMS, a cutting-edge technique for detecting quantum effects in biological systems with high sensitivity. Explore ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme's ligand-binding site, interfering with recognition and binding to the glycosylation proteins' normal glycoprotein ...