In effect, ICS are effective on the many steps of the inflammatory cascade, from the activation of Th2-lymphocytes to the recruitment and eosinophil activation to airway edema. Furthermore ...

Eosinophilic asthma (also known as e-asthma or eos asthma) is a severe form of asthma that causes high levels of eosinophils in the lung tissue, blood, and mucus. Eosinophils are a type of immune ...

Eosinophil activation gives rise to the extracellular release of a number of potent cytotoxic proteins such as eosinophil cationic protein (ECP), believed to play a role in the development of ...

In the course of the ALS development program, however, dexpramipexole was observed to produce a significant and targeted depletion of eosinophils in the blood of ALS patients 4. Eosinophils are ...

IL-5 is a core cytokine in type II inflammation. It promotes the growth and activation of eosinophils, a type of white blood cell involved in the inflammatory response. GSK stock has risen 17.8% ...