In addition, exosome delivery systems struggle with preserving bioactivity and maintaining adaptable miRNA cargoes throughout the entire release period, limiting their effectiveness at different ...

The researcher has given an overview on the regulatory network of extracellular circRNAs in cancer and their impact on cancer drug resistance. In order to propagate malignancy, circRNAs shuttle ...

Another limitation was the lack of an established microRNA control against which to normalize the levels of candidate microRNAs used to develop the signature. An investigational exosome-based ...

microRNA detection in very dilute samples (e.g., urine, CSF) can be boosted by first isolating exosomes in the sample and then profiling microRNAs contained in these extracellular vesicles. The gold ...