What makes BA-MCY unique is that it has the opposite effect, instead of reducing bile production, BA-MCY inhibits FXR and boosts ... gut microbes and intestinal cells underscores a complex ...
Scientists have known for some time that gut bacteria modify bile acids into a form that stimulates a receptor called FXR, which reduces ... enzyme produced by intestinal cells converts bile ...
Scarb2 deficiency is associated with alterations in gut microbiota composition and increased intestinal FXR signaling, leading to impairments in lipid absorption and the renewal of the intestinal ...
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Researchers identify key driver of fibrosis in Crohn's diseaseMore information: Ju-Hyun Ahn et al, Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn's disease, Cell Host & Microbe (2024). DOI: 10.1016/j.chom.2024.11.012 ...
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