Febuxostat 40 mg daily appears to be as efficacious as allopurinol in lowering serum uric acid levels. [38] Both febuxostat 40 and 80 mg can be given to patients with mild-to-moderate renal impair ...

febuxostat 120-mg, and allopurinol groups, respectively. Serious adverse events were reported by 161 patients, with cardiac disorders being reported most frequently by 48 patients, all of whom had ...

Less than 50% reported following initial recommended dosages for allopurinol or febuxostat. Rheumatologists report largely adhering to American College of Rheumatology guidelines for gout ...